Mike, I ran them for about a year or so due to the need of a daily driver for work. No issue at all. They'll drop the ratio almost exactly 1 point this way. More with a thicker gasket like a example of Fel-Pro's .055 thick gasket vs the .039.
Back story;
The only car left was my Cuda, a 360 zero deck piston set up. The rest of the engine was near a strip build. Big tube headers, big(ish) cam , big carb, single plane 4.10's etc...
Since the need to get my butt to work was dyer, this shim was an answer to the pump gas math. (Along with a intake, carb, cam & gear change for traveling 40 miles one way to work. 2.76's are wonderful for mileage!)