What manifold is it?
I have an Eddy performer, and it has both Mopar and SBC pattern bolt holes.
What I did was buy the auto parts store Mr gasket SBC "reuseable" silicon impregnated aluminum SBC gasket for $20, and then a new $20 iron housing from Napa, then elongated the holes on the water neck housing using a slide table on my drill press.
I used no additional sealant of any kind.
So far, so good.
I probably could have bought an SBC water neck, and probably used an aluminum one, but I've had terrible luck with aluminum water necks- not on the intake surface, but under the hose in the clamp area.